MOULDS THE PROCESSED BY ELECTRICAL EROSION

MOULDS THE PROCESSED BY ELECTRICAL EROSION

The phenomenon of electro material dislocation consists of SHORTS two objects electrically conductive at a distance from one another and between which there is an electric potential difference.Suppose two objects (parts) initially at distance and electric potential difference start to be close to each other.Distance that will pierce the dielectric

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Misfolding of a Single Disulfide Bonded Globular Protein into a Low-Solubility Species Conformationally and Biophysically Distinct from the Native One

In practice and despite Anfinsen’s dogma, the refolding of recombinant multiple SS-bonded proteins is famously difficult because misfolded species with non-native SS-bonds appear upon the oxidization of their cysteine residues.On the other hand, single SS-bond proteins are thought to be simple to refold because their cysteines have only one S

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A pan-tumor-siRNA aptamer chimera to block nonsense-mediated mRNA decay inflames and suppresses tumor progression

Immune-checkpoint blockade (ICB) therapy has changed the clinical outcome of many types of aggressive tumors, but there still remain many cancer patients that do not respond to these treatments.There is an unmet need to develop a feasible clinical therapeutic platform to increase the rate of response to ICB.Here we use a previously described clinic

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